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  6. CD41/Integrin alpha 2b Mouse anti-Human, Clone: 6D7C5, Proteintech 

CD41/Integrin alpha 2b Mouse anti-Human, Clone: 6D7C5, Proteintech
SDP

Catalog No. 501736437 Shop All Proteintech Group Inc Products
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150 μL
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50-173-6437 150 μL
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Catalog No. 50-173-6437 Supplier Proteintech Group Inc Supplier No. 603501IG150UL
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Description

Mouse Monoclonal Antibody

CD41 (platelet glycoprotein IIb, ITGA2B) is composed of two subunits -120 kDa a, alpha and 23 kDa b, beta- that interact with CD61 in the presence of calcium to form a functional adhesive protein receptor. CD41 is also involved in blood coagulation by mediating platelet aggregation. Upon blood vessel damage, CD41 binds to a variety of proteins including von Willebrand factor, fibrinogen, fibronectin and vitronectin. CD41 is mainly expressed on megakaryocyte-platelet lineage, but generally belongs to the antigens that are expressed during the early stages of hematopoietic differentiation. Diseases associated with CD41 dysfunction include Glansmann Thrombasthenia, and Platelet type-16 bleeding disorder.

Specifications

Antigen CD41/Integrin alpha 2b
Applications Western Blot
Classification Monoclonal
Clone 6D7C5
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene ITGA2B
Gene Accession No. P08514
Gene Alias CD41, CD41/Integrin alpha 2b, CD41B, GP2B, GPalpha IIb, GPIIb, GTA, HPA3, Integrin alpha IIb, ITGA2B, ITGAB
Gene Symbols ITGA2B
Host Species Mouse
Immunogen Peptide
Purification Method Protein G
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3674
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG1
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