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CD41a Monoclonal Antibody (HIP8), APC-eFluor™ 780, eBioscience™, Invitrogen™
Mouse Monoclonal Antibody
$378.00
Specifications
| Antigen | CD41a |
|---|---|
| Clone | HIP8 |
| Concentration | 5 μL/Test |
| Applications | Flow Cytometry |
| Classification | Monoclonal |
| Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
47-041-942
|
eBioscience
47041942 |
100 Tests |
Each of 1 for $378.00
|
|
|||||
Description
The HIP8 monoclonal antibody reacts with the human CD41 molecule, the integrin alpha IIb also known as platelet GPIIb. CD41 non-covalently associates with integrin beta3 (GPIIIa, CD61) and is expressed by megakaryocytes and platelets. The CD41/CD61 comple
CD41 (platelet glycoprotein IIb, ITGA2B) is composed of two subunits -120 kDa a, alpha and 23 kDa b, beta- that interact with CD61 in the presence of calcium to form a functional adhesive protein receptor. CD41 is also involved in blood coagulation by mediating platelet aggregation. Upon blood vessel damage, CD41 binds to a variety of proteins including von Willebrand factor, fibrinogen, fibronectin and vitronectin. CD41 is mainly expressed on megakaryocyte-platelet lineage, but generally belongs to the antigens that are expressed during the early stages of hematopoietic differentiation. Diseases associated with CD41 dysfunction include Glansmann Thrombasthenia, and Platelet type-16 bleeding disorder.Specifications
| CD41a | |
| 5 μL/Test | |
| Monoclonal | |
| Liquid | |
| RUO | |
| P08514 | |
| IgG1 κ | |
| 4° C, store in dark, DO NOT FREEZE! |
| HIP8 | |
| Flow Cytometry | |
| APC-eFluor 780 | |
| Mouse | |
| Human | |
| 3674 | |
| Primary | |
| Antibody |
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