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CD46 Rabbit anti-Human, Mouse, Polyclonal, Proteintech
SDP

Catalog No. p-7205225 Shop All Proteintech Group Inc Products
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50-172-8022 150 μL
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Catalog No. 50-172-8022 Supplier Proteintech Group Inc Supplier No. 124941AP150UL
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Description

Rabbit Polyclonal Antibody

CD46 (MCP, membrane cofactor protein) is a multifunctional cell surface transmembrane protein that binds and inactivates C3b and C4b complement fragments, regulates T cell-induced inflammatory responses by either inhibiting (CD46-1 isoform) or increasing (CD46-2 isoform) the contact hypersensitivity reaction. CD46 also serves as a receptor for several human pathogens (both bacteria and viruses), and its ligation alteres T lymphocyte polarization toward antigen-presenting cells or target cells, inhibiting lymphocyte function. CD46 is a protector of placental tissue and is also expressed on the inner acrosomal membrane of spermatozoa.

Specifications

Antigen CD46
Applications Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 0.13 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene CD46
Gene Accession No. O88174, P15529
Gene Alias CD46, MCP, Membrane cofactor protein, MIC10, TLX, TRA2.10
Gene Symbols Cd46
Host Species Rabbit
Immunogen CD46 Fusion Protein Ag3131
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 17221, 4179
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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