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Invitrogen™ CD49a (Integrin alpha 1) Polyclonal Antibody
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Catalog No. PIPA579525
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100 μg
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PIPA579525 100 μg
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Catalog No. PIPA579525 Supplier Invitrogen™ Supplier No. PA579525
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Description

Rabbit Polyclonal Antibody

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: human Hela whole cell. IHC: human esophageal squamous carcinoma tissue, human lung adenocarcinoma tissue, human placenta tissue, human liver cancer tissue.

Integrin alpha 1 (ITGA1) chain associates with the beta 1 (ITGB1) chain to form a heterodimer that functions as a dual laminin/collagen receptor in neural cells and hematopoietic cells. ITGA1 has a 206-amino acid I domain in its N-terminal half, followed by 3 divalent cation-binding sites and a C-terminal transmembrane domain with a short cytoplasmic tail. It also has 28 potential N-glycosylation sites. Human ITGA1 was expressed in a mouse fibroblast cell line as a 180-kD protein. ITGA1 is involved in the early remodeling of osteoarthritic cartilage and plays an essential role in the regulation of mesenchymal stem cell proliferation and cartilage production. It also plays an essential role in the regulation of MSC proliferation and cartilage production.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CD49a (Integrin alpha 1)
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 500 μg/mL
Conjugate Unconjugated
Formulation PBS with 4mg trehalose and no preservative
Gene Itga1
Gene Accession No. P18614, P56199, Q3V3R4
Gene Alias CD49 antigen-like family member A; CD49a; E130012M19Rik; integrin alpha 1; integrin alpha-1; integrin subunit alpha 1; integrin, alpha 1; Itga1; Laminin and collagen receptor; very late activation protein 1; Vla1; VLA-1
Gene Symbols Itga1
Host Species Rabbit
Immunogen A synthetic peptide corresponding to a sequence at the C-terminus of human Integrin alpha 1 (1121-1134aa SNQKRELAIQISKD).
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 109700, 25118, 3672
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Lyophilized
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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