CD49c (Integrin alpha 3) Mouse anti-Human, FITC, Clone: 17C6, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA528110
This antibody recognizes a 150 kDa cell surface antigen which is also known as the alpha-3 integrin and as VLA-3. CD49c is very weakly expressed on peripheral blood leucocytes and is not found on platelets. Epithelial cells and endothelial cells express significant levels of CD49c.CD49c (ITGA3) is involved in interstitial lung disease, nephrotic syndrome, and epidermolysis bullosa, congenital (ILNEB). A multiorgan disorder characterized by congenital nephrotic syndrome, interstitial lung disease, and epidermolysis bullosa. The respiratory and renal features predominate, and lung involvement accounts for the lethal course of the disease. The disease is caused by mutations affecting the gene represented in this entry.
|CD49c (Integrin alpha 3)|
|PBS with 1% BSA and 0.09% sodium azide|
|CD49c transfected cell line|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Store in the dark.|
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