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BD AbSeq™ CD64 Mouse, anti-Human, Oligo, Clone: 10.1, BD AbSeq™

Catalog No. BDB940023 Shop All BD Biosciences Products
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BDB940023 25 Tests
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Catalog No. BDB940023 Supplier BD AbSeq™ Supplier No. 940023
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Description

Mouse Monoclonal Antibody

The 10.1 monoclonal antibody specifically binds to CD64, a 72 kDa type I transmembrane glycoprotein that is a high affinity receptor for human IgG (FcγRI), especially the IgG1 and IgG3 subclasses. CD64 is expressed on monocytes, macrophages, dendritic cells, granulocytes activated with interferon-gamma and early myeloid lineage cells. CD64 associates with a signaling FcRγ homodimer to form the functional high affinity FcγRI complex. CD64 functions in both innate and adaptive immune responses and mediates endocytosis, phagocytosis, antigen presentation, antibody-dependent cellular toxicity, cytokine release and superoxide generation.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD64
Applications Single Cell 3' Sequencing
Clone 10.1
Conjugate Oligo
Host Species Mouse
Quantity 25 Tests
Regulatory Status RUO
Primary or Secondary Primary
Target Species Human
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