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CD65 Mouse anti-Human, FITC, Clone: VIM8, eBioscience™ Non-distribution product as customer accommodation.

Mouse Monoclonal Antibody

$127.00 - $324.00

Specifications

Antigen CD65
Clone VIM8
Target Species Human
Conjugate FITC
Isotype IgM
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Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
50-245-237 Non-distribution product as customer accommodation.
View Documents
Invitrogen
11065941
25 Tests
Each for $127.00
Add to cart
 
50-245-238 Non-distribution product as customer accommodation.
View Documents
Invitrogen
11065942
100 Tests
Each for $324.00
Add to cart
 
Description

Description

Description: This VIM8 antibody reacts with the desialylated asialoganglioside of human CD65. This type 2 fucosylated carbohydrate antigen is expressed on the surface of all myeloid cells during development. Moreover, CD65 is expressed highly on granulocytes and weakly on monocytes in peripheral blood. CD65 has been reported to be a ligand for CD62E (E-Selectin). However, the sialylated form of CD65 (designated CD65s) can be used as a marker for acute myeloid leukemia (AML) as its expression increases as CD34 decreases. Finally, CD65 is important for extravascular infiltration of AML cells. Applications Reported: This VIM8 antibody has been reported for use in flow cytometric analysis. Applications Tested: This VIM8 antibody has been pre-titrated and tested by flow cytometric analysis of normal human peripheral blood cells. This can be used at 5 µL (0.25 µg) per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. Excitation: 488 nm; Emission: 520 nm; Laser: Blue Laser. Filtration: 0.2 µm post-manufacturing filtered.

This type 2 fucosylated carbohydrate antigen is expressed on the surface of all myeloid cells during development. Moreover, CD65 is expressed highly on granulocytes and weakly on monocytes in peripheral blood. CD65 has been reported to be a ligand for CD62E (E-Selectin). However, the sialylated form of CD65 (designated CD65s) can be used as a marker for acute myeloid leukemia (AML) as its expression increases as CD34 decreases. Finally, CD65 is important for extravascular infiltration of AML cells.
Specifications

Specifications

CD65
Human
IgM
Monoclonal
Liquid
Antibody
4° C, store in dark, DO NOT FREEZE!
VIM8
FITC
Flow Cytometry
Primary
Monoclonal
PBS with 0.1% gelatin, 0.2% BSA and 0.09% sodium azide; pH 7.2
RUO
SDS

For Research Use Only.

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