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Invitrogen™ CD68 Polyclonal Antibody
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Catalog No. PIPA589134
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100 μL
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PIPA589134 100 μL
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Catalog No. PIPA589134 Supplier Invitrogen™ Supplier No. PA589134
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Description

Rabbit Polyclonal Antibody

Positive Samples: Mouse fat, Mouse skin, Rat skin; Cellular Location: Cell membrane, Endosome membrane, Lysosome membrane, Single-pass type I membrane protein, Single-pass type I membrane protein Immunogen sequence: NDCPHKKSAT LLPSFTVTPT VTESTGTTSH RTTKSHKTTT HRTTTTGTTS HGPTTATHNP TTTSHGNVTV HPTSNSTATS QGPSTATHSP ATTSHGNATV HPTSNSTATS PGFTSSAHPE PPPPSPSPSP TSKETIGDYT WTNGSQPCVH LQAQIQIRVM YTTQGGGEAW GISVLNPNKT KVQGSCEGAH PHLLLSFPYG HLSFGFMQDL QQKVVYLSYM AVEYNVSFPH AAQWTFSAQN ASLRDLQAPL GQSFSCSNSS IILSPAVHLD LLSLRLQAAQ LPHTGVFGQS FSCPSDRS.

CD68 (Macrosialin) is a 110 kDa integral membrane glycoprotein predominantly expressed on the intracellular lysomsomes of monocytes and macrophages and to a lesser extent by dendritic cells and peripheral blood granulocytes. Also, CD68 could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. CD68 is expressed by interdigitating reticulum cells in tonsil and some histiocytic lymphoma or histiocytosis, acute myeloid leukemia (AML), and granulocytic sarcoma. Elevated expression of CD68 has been demonstrated on CD34+ cells in various human malignancies, including several Acute Myeloid Leukemia studies.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CD68
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.57 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.09% sodium azide; pH 7.3
Gene Cd68
Gene Accession No. P34810
Gene Alias CD68; CD68 antigen; CD68 molecule; GP110; Lamp4; macrophage antigen CD68; macrosialin; Scard1; scavenger receptor class D, member 1; similar to CD68 antigen
Gene Symbols Cd68
Host Species Rabbit
Immunogen Synthetic peptide.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 968
Target Species Human, Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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