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CD68 Polyclonal Antibody, Rockland™
SDP

Catalog No. p-7191051
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100 μg
25 μL
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Catalog No. Quantity
50-199-2344 100 μg
50-199-2345 25 μL
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Catalog No. 50-199-2344 Supplier Rockland Immunochemicals Supplier No. 600401MP2
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Description

Rabbit Polyclonal Antibody

Store vial at -20°C prior to opening. Aliquot contents and freeze at -20°C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. Anti-CD68 Antibody is directed against mouse CD68 protein. A BLAST analysis was used to suggest reactivity with this protein from mouse based on 100% homology for the immunogen sequence. Cross reactivity with Cd68 from other sources has not been determined.

CD68 (Macrosialin) is a 110 kDa integral membrane glycoprotein predominantly expressed on the intracellular lysomsomes of monocytes and macrophages and to a lesser extent by dendritic cells and peripheral blood granulocytes. Also, CD68 could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. CD68 is expressed by interdigitating reticulum cells in tonsil and some histiocytic lymphoma or histiocytosis, acute myeloid leukemia (AML), and granulocytic sarcoma. Elevated expression of CD68 has been demonstrated on CD34+ cells in various human malignancies, including several Acute Myeloid Leukemia studies.

Specifications

Antigen CD68
Applications ELISA, Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 1.02 mg/mL
Conjugate Unconjugated
Formulation 0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Cd68
Gene Accession No. P31996
Gene Alias BOS_18923; CD68; CD68 antigen; CD68 molecule; Gp110; Lamp4; macrophage antigen CD68; Macrosialin; Scard1; scavenger receptor class D, member 1
Gene Symbols Cd68
Host Species Rabbit
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 12514
Target Species Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
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