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CD71 Mouse, anti-Mouse, R718, Clone: C2, BD OptiBuild™

Catalog No. BDB752004 Shop All BD Biosciences Products
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BDB752004 50 μg
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Catalog No. BDB752004 Supplier BD Biosciences Supplier No. 752004
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Description

Mouse Monoclonal Antibody

The C2 monoclonal antibody specifically binds to CD71, the transferrin receptor. CD71 is a disulfide-linked homodimer of 95-kDa subunits. CD71 mediates one of the cellular mechanisms for iron uptake, and its expression is regulated according to the cell's iron requirements. It is expressed at high levels on developing erythroid cells, and it is upregulated after mitogenic activation of B or T lymphocytes. The C2 monoclonal antibody selectivity inhibits some types of T- and B-cell activation by down-regulation of transferrin receptor expression, but it does not block binding of transferrin.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD71
Applications Flow Cytometry
Classification Monoclonal
Clone C2
Conjugate R718
Host Species Mouse
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Mouse
Content And Storage Refrigerate Upon Arrival
Form Liquid
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