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Invitrogen™ CD79a Monoclonal Antibody (HM57), FITC
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Catalog No. PIMA528540
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100 Tests
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PIMA528540 100 Tests
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Catalog No. PIMA528540 Supplier Invitrogen™ Supplier No. MA528540
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Description

Mouse Monoclonal Antibody

This antibody The antibody HM57 interacts with intracellular domain of CD79a (Ig alpha), a 40-45 kDa subunit of B cell antigen-specific receptor (BCR) and its early developmental forms. Recommended dilution is for 100 μL of whole blood or 1x10^6 cells in suspension.

CD79a is a disulphide-linked heterodimer that includes B29 (CD79b) polypeptide. CD79a is a B lymphocyte antigen receptor with an antigen-specific surface component Ig (immunoglobulin) that associates with Ig-alpha and Ig-beta, necessary elements for the expression and function of the B-cell antigen receptor. CD79a first appears at pre-B cell stage and persists until the plasma cell stage where it is found as an intracellular component. CD79a is found in the majority of acute leukemias of precursor B cell type, in B cell lines, B cell lymphomas, and in some myelomas. It is not present in myeloid or T cell lines. Diseases associated with CD79a include Agammaglobulinemia 3 and Agammaglobulinemia, Non-Bruton type.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CD79a
Applications Flow Cytometry
Classification Monoclonal
Clone HM57
Concentration 55 μg/mL
Conjugate FITC
Formulation PBS with 0.2% BSA and 15mM sodium azide; pH 7.4
Gene CD79A
Gene Accession No. P11911, P11912, P40293
Gene Alias B-cell antigen receptor; B-cell antigen receptor complex-associated protein alpha chain; B-cell antigen receptor complex-associated protein alpha chain-like; CD79; CD79a; CD79A antigen (immunoglobulin-associated alpha); CD79a molecule; CD79a molecule, immunoglobulin-associated alpha; CD79A protein; CD79-alpha protein; EGK_10665; Ig alpha; IGA; Igalpha; ig-alpha; immunoglobulin-associated alpha; LOC100913063; Ly54; Ly-54; MB1; MB-1; MB-1 membrane glycoprotein; Membrane-bound immunoglobulin-associated protein; surface IgM-associated protein
Gene Symbols CD79A
Host Species Mouse
Immunogen Synthetic peptide corresponding to amino acids 202-216 human CD79a.
Purification Method Size-exclusion chromatography
Quantity 100 Tests
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100052219, 100190992, 100724815, 100913063, 12518, 281674, 973
Target Species Bovine, Chicken, Horse, Guinea Pig, Human, Marsupial, Mouse, Pig, Rabbit, Rodent, Rat
Content And Storage 4°C, store in dark, DO NOT FREEZE!
Product Type Antibody
Form Liquid
Isotype IgG1
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