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Invitrogen™ CD9 Monoclonal Antibody (MM2/57)
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Catalog No. AHS0902
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AHS0902 100 μg
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Catalog No. AHS0902 Supplier Invitrogen™ Supplier No. AHS0902
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Description

Mouse Monoclonal Antibody

CD9 Monoclonal Antibody for Flow, IHC, IP, Western Blot

CD9 antigen is a glycoprotein expressed on the surface of developing B lymphocytes, platelets, monocytes, eosinophils, basophil, stimulated T lymphocytes and by neurons and glial cells in the peripheral nervous system. CD9 belongs to a family of membrane proteins termed tetraspanins which transverse the membrane four times. In pre B cells and platelets, CD9 antigen regulates cell activation and aggregation possibly through an association with the integrin CD41 / CD61 (GPIIb / GPIIIa). CD9 is involved in cell motility, osteoclastogenesis, neurite outgrowth, myotube formation, and sperm-egg fusion, plays roles in cell attachment and proliferation and is necessary for association of heterologous MHC II molecules on the dendritic cell plasma membrane which is important for effective T cell stimulation. CD9 functions in many cellular processes including differentiation, adhesion, and signal transduction, and expression plays a critical role in the suppression of cancer cell motility and metastasis. CD9 is also considered as metastasis suppressor in solid tumors.
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Specifications

Antigen CD9
Applications Flow Cytometry, Immunohistochemistry, Immunoprecipitation, Western Blot
Classification Monoclonal
Clone MM2/57
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.1% BSA and 0.1% sodium azide
Gene CD9
Gene Accession No. P21926, P40240
Gene Alias 5H9; 5H9 antigen; antigen CD9; BA2; BA-2/p24 antigen; BTCC-1; CD9; CD9 antigen; CD9 antigen (p24); CD9 molecule; cell growth-inhibiting gene 2 protein; DRAP-27; GIG2; Leukocyte antigen MIC3; MIC3; motility related protein-1; Motility-related protein; MRP-1; p24; sCD 9; sCD9; soluble CD 9; soluble CD9; Tetraspanin29; Tetraspanin-29; transmembrane protein CD9; TSPAN29; Tspan-29
Gene Symbols CD9
Host Species Mouse
Immunogen Human platelet glycoprotein.
Purification Method Protein A
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100345844, 12527, 928
Target Species Human, Mouse, Rabbit
Content And Storage 4°C
Product Type Antibody
Form Liquid
Isotype IgG2b κ
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