Invitrogen™ CD90 Monoclonal Antibody (AF-9)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA135307

Catalog No. 01-671-269

Description

CD90 (Thy-1) is an 18-35 kDa GPI-anchored glycoprotein and a member of the immunoglobulin superfamily. It may contribute to inhibition of proliferation/differentiation of hematopoietic stem cells and neuron memory formation in the CNS. It consists of a single Ig domain (112 amino acids; 25-35 kDa) inserted into the cell membrane via a GPI-anchor. Expressed by hematopoietic stem cells and neurons in all species studied. Its highly expressed in connective tissue and various fibroblasts and stromal cell lines, expressed only on small % fetal thymocytes, 10-40% of CD34+ cells in bone marrow, and.

CD90 (Thy 1) antigen is a GPI linked glycoprotein member of the Immunoglobulin super family. CD90 is expressed in murine T cells, thymocytes, neural cells, Kupffer's cells and fibroblasts. CD90 may play a role in cell-cell or cell-ligand interactions during synaptogenesis and other events in the brain. CD90 can be used as a marker for a variety of stem cells and for the axonal processes of mature neurons. Structural study of CD90 led to the foundation of the Immunoglobulin superfamily, of which it is the smallest member, and led to the first biochemical description and characterization of a vertebrate GPI anchor. Diseases associated with CD90 dysfunction include nasopharyngeal carcinoma and thymoma.

Specifications

• Antigen: CD90
• Classification: Monoclonal
• Concentration: 0.1 mg/mL
• Formulation: PBS with 0.02% sodium azide
• Gene Accession No.: P04216
• Gene Symbols: Thy1
• Immunogen: T cell lymphoma cells.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Bovine
• Product Type: Antibody
• Isotype: IgG1

• Applications: Flow Cytometry, Immunohistochemistry (Frozen)
• Clone: AF-9
• Conjugate: Unconjugated
• Gene: Thy1
• Gene Alias: CD7; CD90; CDw90; FLJ33325; membrane glycoprotein; T25; Thy 1.2; THY1; Thy-1; Thy-1 antigen; Thy-1 cell surface antigen; thy-1 glycoprotein; thy-1 membrane glycoprotein; Thy-1 protein; Thy-1 T-cell antigen; Thy1.1; Thy1.2; Thy-1.2; thymus cell antigen 1, theta; Thymus cell surface antigen
• Host Species: Mouse
• Purification Method: Purified
• Regulatory Status: RUO
• Gene ID (Entrez): 614712, 7070
• Content And Storage: 4°C
• Form: Liquid