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Invitrogen™ CD90 Monoclonal Antibody (AF-9)
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Catalog No. 01671269
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100 μg
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Catalog No. Quantity
01-671-269 100 μg
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Catalog No. 01-671-269 Supplier Invitrogen™ Supplier No. MA135307
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Description

Mouse Monoclonal Antibody

CD90 (Thy-1) is an 18-35 kDa GPI-anchored glycoprotein and a member of the immunoglobulin superfamily. It may contribute to inhibition of proliferation/differentiation of hematopoietic stem cells and neuron memory formation in the CNS. It consists of a single Ig domain (112 amino acids; 25-35 kDa) inserted into the cell membrane via a GPI-anchor. Expressed by hematopoietic stem cells and neurons in all species studied. Its highly expressed in connective tissue and various fibroblasts and stromal cell lines, expressed only on small % fetal thymocytes, 10-40% of CD34+ cells in bone marrow, and.

CD90 (Thy 1) antigen is a GPI linked glycoprotein member of the Immunoglobulin super family. CD90 is expressed in murine T cells, thymocytes, neural cells, Kupffer's cells and fibroblasts. CD90 may play a role in cell-cell or cell-ligand interactions during synaptogenesis and other events in the brain. CD90 can be used as a marker for a variety of stem cells and for the axonal processes of mature neurons. Structural study of CD90 led to the foundation of the Immunoglobulin superfamily, of which it is the smallest member, and led to the first biochemical description and characterization of a vertebrate GPI anchor. Diseases associated with CD90 dysfunction include nasopharyngeal carcinoma and thymoma.
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Specifications

Antigen CD90
Applications Flow Cytometry, Immunohistochemistry (Frozen)
Classification Monoclonal
Clone AF-9
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene Thy1
Gene Accession No. P04216
Gene Alias CD7; CD90; CDw90; FLJ33325; membrane glycoprotein; T25; Thy 1.2; THY1; Thy-1; Thy-1 antigen; Thy-1 cell surface antigen; thy-1 glycoprotein; thy-1 membrane glycoprotein; Thy-1 protein; Thy-1 T-cell antigen; Thy1.1; Thy1.2; Thy-1.2; thymus cell antigen 1, theta; Thymus cell surface antigen
Gene Symbols Thy1
Host Species Mouse
Immunogen T cell lymphoma cells.
Purification Method Purified
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 614712, 7070
Target Species Human, Bovine
Content And Storage 4°C
Product Type Antibody
Form Liquid
Isotype IgG1
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