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Invitrogen™ CD97 Monoclonal Antibody (MEM-180), FITC

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA119585

Catalog No. 01-676-315


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Description

Description

This antibody recognizes a unique epitope on CD97, a 75-85 kDa surface glycoprotein of G-protein-coupled receptor family, expressed on activated B and T lymphocytes, monocytes/macrophages, dendritic cells and granulocytes.

CD97 is a G-protein-coupled seven-span transmembrane adhesive receptor that is constitutively expressed on granulocytes and monocytes and rapidly upregulated on T and B cells upon activation. CD97 is produced in alternatively spliced forms and its cellular ligand is CD55 (DAF), which protects various cell types from complement-mediated damage. Interaction of CD97 on leukocytes and CD55 on vessel cells probably facilitate leukocyte activation and migration into the tissues, similarly, CD97 seems to play a role in tumour migration and invasiveness. CD97 is involved in T cell regulation and peripheral granulocyte homeostasis.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

CD97
Monoclonal
FITC
ADGRE5
AA409984; Adgre5; adhesion G protein-coupled receptor E5; Cd97; CD97 antigen; CD97 antigen subunit alpha; CD97 antigen subunit beta; CD97 molecule; EGF-TM7 receptor; leukocyte antigen CD97; seven transmembrane helix receptor; seven-span transmembrane protein; seven-transmembrane, heterodimeric receptor associated with inflammation; TM7LN1
Mouse
Size-exclusion chromatography
RUO
976
4°C, store in dark, DO NOT FREEZE!
Liquid
Flow Cytometry
MEM-180
PBS with 0.2% BSA and 15mM sodium azide; pH 7.4
P48960
ADGRE5, CD97
PHA-activated PBL.
100 Tests
Primary
Human
Antibody
IgG1
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