Invitrogen™ Cdc20 Monoclonal Antibody (BA8)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA146040

Catalog No. PIMA146040

Description

Cdc20 Monoclonal Antibody for Western Blot, Flow, ELISA

Required for full ubiquitin ligase activity of the anaphase promoting complex/cyclosome (APC/C) and may confer substrate specificity upon the complex. Is regulated by MAD2L1: in metaphase the MAD2L1-CDC20-APC/C ternary complex is inactive and in anaphase the CDC20-APC/C binary complex is active in degrading substrates. The CDC20-APC/C complex positively regulates the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons. CDC20-APC/C-induced degradation of NEUROD2 induces presynaptic differentiation.

Specifications

• Antigen: Cdc20
• Classification: Monoclonal
• Concentration: 1.0 mg/mL
• Formulation: PBS with 0.02% sodium azide
• Gene Accession No.: 0
• Gene Symbols: cdc20.S
• Immunogen: Synthetic C terminal peptide (Xenopus laevis). BLAST 'FEVDPVTKKEKEKARSSKSIIHQSIR'.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Frog
• Product Type: Antibody
• Isotype: IgG2a

• Applications: ELISA, Flow Cytometry, Western Blot
• Clone: BA8
• Conjugate: Unconjugated
• Gene: cdc20.S
• Gene Alias: 2310042N09Rik; bA276H19.3; C87100; cdc20; CDC20 cell division cycle 20 homolog; cdc20.S; CDC20A; cell cycle protein p55CDC; cell division cycle 20; cell division cycle 20 homolog; cell division cycle 20 S homeolog; cell division cycle protein 20 homolog; fizzy1; mmCdc20; p55cdc; XELAEV_18025163mg; X-FZY
• Host Species: Mouse
• Purification Method: Protein A/G
• Regulatory Status: RUO
• Gene ID (Entrez): 379130
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

Safety and Handling

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