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Invitrogen™ Cdc20 Monoclonal Antibody (BA8)
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Catalog No. PIMA146040
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100 μg
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Catalog No. Quantity
PIMA146040 100 μg
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Catalog No. PIMA146040 Supplier Invitrogen™ Supplier No. MA146040
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Description

Mouse Monoclonal Antibody

Cdc20 Monoclonal Antibody for Western Blot, Flow, ELISA

Required for full ubiquitin ligase activity of the anaphase promoting complex/cyclosome (APC/C) and may confer substrate specificity upon the complex. Is regulated by MAD2L1: in metaphase the MAD2L1-CDC20-APC/C ternary complex is inactive and in anaphase the CDC20-APC/C binary complex is active in degrading substrates. The CDC20-APC/C complex positively regulates the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons. CDC20-APC/C-induced degradation of NEUROD2 induces presynaptic differentiation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Cdc20
Applications ELISA, Flow Cytometry, Western Blot
Classification Monoclonal
Clone BA8
Concentration 1.0 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene cdc20.S
Gene Accession No. 0
Gene Alias 2310042N09Rik; bA276H19.3; C87100; cdc20; CDC20 cell division cycle 20 homolog; cdc20.S; CDC20A; cell cycle protein p55CDC; cell division cycle 20; cell division cycle 20 homolog; cell division cycle 20 S homeolog; cell division cycle protein 20 homolog; fizzy1; mmCdc20; p55cdc; XELAEV_18025163mg; X-FZY
Gene Symbols cdc20.S
Host Species Mouse
Immunogen Peptide from the carboxy terminus of the protein.
Purification Method Protein A
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 379130
Target Species Frog
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG2a
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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