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Invitrogen™ Cdc23 Recombinant Rabbit Monoclonal Antibody (1Q2I3)
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Catalog No. PIMA538158
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PIMA538158 100 μL
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Catalog No. PIMA538158 Supplier Invitrogen™ Supplier No. MA538158
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Description

Rabbit Recombinant Monoclonal Antibody

Positive Samples: HeLa, SKOV3, Jurkat, Mouse lung, Mouse brain, Mouse spleen, Rat brain Immunogen sequence: YSCGEIVEHL EESTAFRYLA QYYFKCKLWD EASTCAQKCC AFNDTREEGK ALLRQILQLR NQGETPTTEV PAPFFLPASL SANNTPTRRV SPLNLSSVTP.

Ubiquitination is an important mechanism through which three classes of enzymes act in concert to target short-lived or abnormal proteins for destruction. The three classes of enzymes involved in ubiquitination are the ubiquitin-activating enzymes (E1s), the ubiquitin-conjugating enzymes (E2s) and the ubiquitin-protein ligases (E3s). Ubr2 (Ubiquitin-protein ligase E3-alpha-2), also known as N-recognin-2, is a 1755 amino acid protein that contains one UBR-type zinc finger and one RING-type zinc finger. Participating in protein modification events within the N-end rule pathway, Ubr2 functions as an E3 ubiquitin-protein ligase that recognizes and binds proteins that contain destabilizing N-terminal residues, thereby leading to their ubiquitination and subsequent degradation. Mice lacking Ubr2 are infertile due to defects in male meiosis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Cdc23
Applications ELISA, Western Blot, Immunocytochemistry
Classification Recombinant Monoclonal
Clone 1Q2I3
Concentration 1.55 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Cdc23
Gene Accession No. Q8BGZ4, Q9UJX2
Gene Alias 6030435O18; ANAPC8; anaphase promoting complex subunit 8; anaphase-promoting complex subunit 8; APC8; CDC23; CDC23 (cell division cycle 23, yeast, homolog); CDC23 cell division cycle 23; cell division cycle 23; cell division cycle 23 homolog; cell division cycle protein 23; cell division cycle protein 23 homolog; CUT23; cyclosome subunit 8; D18Ertd243e; zgc:56013
Gene Symbols Cdc23
Host Species Rabbit
Immunogen A synthetic peptide corresponding to a sequence within amino acids 498-597 of human CDC23 (Q9UJX2).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 291689, 52563, 8697
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

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