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CDC25A Rabbit anti-Human, Mouse, Polyclonal, Proteintech
SDP

Catalog No. 501735945 Shop All Proteintech Group Inc Products
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50-173-5945 150 μL
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Catalog No. 50-173-5945 Supplier Proteintech Group Inc Supplier No. 550311AP150UL
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Description

Rabbit Polyclonal Antibody

The antibody is specific to CDC25A.

Replication factor C (RFC) is an essential DNA polymerase accessory protein that is required for numerous aspects of DNA metabolism, including DNA replication, DNA repair and telomere metabolism. RFC is a heteropentameric complex that recognizes a primer on a template DNA, binds to a primer terminus and loads proliferating cell nuclear antigen (PCNA) onto DNA at primer-template junctions in an ATP-dependent reaction. All five of the RFC subunits share a set of related sequences (RFC boxes) that include nucleotidebinding consensus sequences. Four of the five RFC genes (RFC1, RFC2, RFC3 and RFC4) have consensus ATP-binding motifs. The small RFC proteins, RFC2, RFC3, RFC4 and RFC5, interact with Rad24, whereas the RFC1 subunit does not. RFC2, the third-largest subunit of the RFC complex, exhibits ATP binding which makes it important for both DNA replication and checkpoint function.

Specifications

Antigen CDC25A
Applications Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 0.53 mg/mL
Conjugate Unconjugated
Formulation 0.1 M glycine, 0.1 M sodium bicarbonate with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene CDC25A
Gene Accession No. P30304, P48964
Gene Alias CDC25A, CDC25A2, M phase inducer phosphatase 1
Gene Symbols Cdc25a
Host Species Rabbit
Immunogen Peptide
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 12530, 993
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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