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Invitrogen™ Cdc42EP2 Polyclonal Antibody
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Catalog No. PIPA531049
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100 μL
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PIPA531049 100 μL
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Catalog No. PIPA531049 Supplier Invitrogen™ Supplier No. PA531049
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: mouse heart. Predicted reactivity: Mouse (89%), Rat (87%), Rhesus Monkey (99%), Bovine (88%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Cdc42, a small GTPase, regulates Actin polymerization, elongation of cell shape and cell signaling through interactions with many different downstream effector proteins, most of which contain a Cdc42-binding motif known as a CRIB domain. Cdc42EP2 (Cdc42 effector protein 2), also known as BORG1 or CEP2, is a 210 amino acid intracytoplasmic protein that localizes to both the cytoplasm and the cytoskeleton and contains one CRIB domain. Highly expressed in heart and present at lower levels in liver and pancreas, Cdc42EP2 interacts with Cdc42 and is thought to be involved in the organization of the Actin cytoskeleton and may also influence Actin filament assembly and overall cell shape.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Cdc42EP2
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Gene CDC42EP2
Gene Accession No. O14613, Q8JZX9
Gene Alias 1110008C05Rik; binder of Rho GTPases 1; Borg1; CDC42 effector protein (Rho GTPase binding) 2; CDC42 effector protein 2; CDC42EP2; CEP2; CRIB-containing BOGR1 protein; D19Bwg1013e
Gene Symbols CDC42EP2
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human CDC42EP2. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 104252, 10435
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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