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Cdc6 Monoclonal Antibody (DCS-180), Invitrogen™

Catalog No. PIMA514314
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500 μL
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Catalog No. Quantity
PIMA514314 500 μL
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Catalog No. PIMA514314 Supplier Thermo Scientific Supplier No. MA514314
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Description

Mouse Monoclonal Antibody

MA5-14314 targets CDC6 in IP and WB applications and shows reactivity with Human samples. The MA5-14314 immunogen is recombinant human CDC6 protein.

The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Cdc6, a protein essential for the initiation of DNA replication. This protein functions as a regulator at the early steps of DNA replication. It localizes in cell nucleus during cell cyle G1, but translocates to the cytoplasm at the start of S phase. The subcellular translocation of this protein during cell cyle is regulated through its phosphorylation by Cdks. Transcription of this protein was reported to be regulated in response to mitogenic signals through transcriptional control mechanism involving E2F proteins.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Cdc6
Applications Immunoprecipitation, Western Blot
Classification Monoclonal
Clone DCS-180
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4
Gene CDC6
Gene Accession No. Q99741
Gene Alias CDC18(S.pombe); CDC18L; cdc18-related protein; CDC6; CDC6 cell division cycle 6 homolog; CDC6-related protein; Cell division control protein 6 homolog; cell division cycle 6; cell division cycle 6 homolog; HsCDC18; HsCDC6; p62(cdc6)
Gene Symbols CDC6
Host Species Mouse
Immunogen Recombinant human CDC6 protein
Purification Method Protein G
Quantity 500 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 990
Target Species Human
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG1
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