CDC6 Mouse anti-Human, Mouse, Rat, Clone: 6F12D2, Proteintech

Mouse Monoclonal Antibody

Supplier:  Proteintech Group Inc 660211IG150UL

Catalog No. 50-173-6464

Description

This antibody is a mouse monoclonal antibody raised against residues near the C terminus of human CDC6.

The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Cdc6, a protein essential for the initiation of DNA replication. This protein functions as a regulator at the early steps of DNA replication. It localizes in cell nucleus during cell cyle G1, but translocates to the cytoplasm at the start of S phase. The subcellular translocation of this protein during cell cyle is regulated through its phosphorylation by Cdks. Transcription of this protein was reported to be regulated in response to mitogenic signals through transcriptional control mechanism involving E2F proteins.

Specifications

• Antigen: CDC6
• Classification: Monoclonal
• Concentration: 0.75 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: O89033, Q99741
• Gene Symbols: Cdc6
• Immunogen: CDC6 Fusion Protein Ag17958
• Quantity: 150 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG1

• Applications: Immunocytochemistry, Immunofluorescence, Western Blot
• Clone: 6F12D2
• Conjugate: Unconjugated
• Gene: CDC6
• Gene Alias: Cdc18 related protein, CDC18L, CDC6, CDC6 related protein, HsCDC18, HsCDC6, p62(cdc6)
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 23834, 360621, 990
• Content And Storage: -20°C
• Form: Liquid