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Invitrogen™ CDH8 Polyclonal Antibody
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Catalog No. PIPA553253
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100 μL
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PIPA553253 100 μL
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Catalog No. PIPA553253 Supplier Invitrogen™ Supplier No. PA553253
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: TLTVTLTDVN DNPPKFAQSL YHFSVPEDVV LGTAIGRVKA NDQDIGENAQ SSYDIIDGDG TALFEITSDA QAQDGIIRLR KPLDFETKKS YTLKVEAANV HIDPRFSGRG PFKDTAT Highest antigen sequence identity to the following orthologs: Mouse - 97%, Rat - 98%.

CDH8 is a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. The extracellular domain consists of 5 subdomains, each containing a cadherin motif, and appears to determine the specificity of the protein's homophilic cell adhesion activity. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. This particular cadherin is expressed in brain and is putatively involved in synaptic adhesion, axon outgrowth and guidance.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CDH8
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene CDH8
Gene Accession No. P55286
Gene Alias AI851472; cad8; CADH8; Cadherin; cadherin 8; cadherin 8, type 2; Cadherin8; cadherin-8; Cdh8; Nbla04261
Gene Symbols CDH8
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human CDH8. Recombinant protein control fragment (Product #RP-90619).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1006
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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