CDK5RAP3 Rabbit anti-Human, Polyclonal, Proteintech

Catalog No.	Quantity
50-172-6789	150 μL

Catalog No. 50-172-6789 Supplier Proteintech Group Inc Supplier No. 110071AP150UL

Description

Rabbit Polyclonal Antibody

The protein encoded by this gene is one of the highly conserved mini-chromosome maintece proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre-RC) and it may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein can interact with MCM2 and MCM6, as well as with the origin recognition protein ORC2. It is regulated by proteolysis and phosphorylation in a cell cycle-dependent manner. Studies of a similar protein in Xenopus suggest that the chromatin binding of this protein at the onset of DNA replication is after pre-RC assembly and before origin unwinding. Alternatively spliced transcript variants encoding distinct isoforms have been identified.

Specifications

• Antigen: CDK5RAP3
• Applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Classification: Polyclonal
• Concentration: 0.13 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene: CDK5RAP3
• Gene Accession No.: Q96JB5
• Gene Alias: C53, CDK5RAP3, HSF 27, IC53, LZAP, MST016, OK/SW cl.114, PP1553, Protein HSF 27
• Gene Symbols: CDK5RAP3
• Host Species: Rabbit
• Immunogen: CDK5RAP3 Fusion Protein Ag1474
• Purification Method: Antigen Affinity Chromatography
• Quantity: 150 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 80279
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG