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Invitrogen™ CDKN2B Monoclonal Antibody (DCS114.1)
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Catalog No. 01670987
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100 μg
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Catalog No. Quantity
01-670-987 100 μg
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Catalog No. 01-670-987 Supplier Invitrogen™ Supplier No. MA112294
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Description

Mouse Monoclonal Antibody

CDKN2B Monoclonal Antibody for Western Blot, ICC/IF, IHC (P), IP

The four known 15-to 19 kDa INK4 proteins (p15INK4b, p16INK4a, p18INK4c andp19INK4d) bind and inhibit CDK4 and CDK6 but not other CDKs, including cyclin E-Cdk2, cyclin A-Cdk2 and cyclin B-Cdk1. Like the three D-type cyclins, the INK4 genes are expressed in distinct tissue-specific patterns, suggesting that they are not strictly redundant. 5 p18INK4c is expressed during G1 to S transition in the eukaryotic cell division cycle. It is maximally induced as cells enter S-phase.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CDKN2B
Applications Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry
Classification Monoclonal
Clone DCS114.1
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.08% sodium azide
Gene CDKN2B
Gene Accession No. P42772
Gene Alias AV083695; CDK inhibitory protein; CDK4B inhibitor; CDK4I; Cdkn2b; cyclin dependent kinase inhibitor 2B; Cyclin dependent kinase inhibitor 2B (p15, inhibits CDK4); cyclin-dependent kinase 4 inhibitor B; cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4); cyclin-dependent kinase inhibitor p15; cyclin-dependent kinase inhibitor p15INK4b; cyclin-dependent kinase inhibitor protein; cyclin-dependent kinases 4 and 6 binding protein; Ink4; INK4B; MTS2; MTS-2; Multiple tumor suppressor 2; p14_CDK inhibitor; p14_INK4B; p14-INK4b; P15; p15 CDK inhibitor; p15(INK4b); p15_INK4B; p15INK4b; p15-INK4b; TP15
Gene Symbols CDKN2B
Host Species Mouse
Immunogen His-tagged recombinant full length p15 protein.
Purification Method Ammonium Sulfate Precipitation
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1030
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG1
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WARNING: Cancer - www.P65Warnings.ca.gov
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