Invitrogen™ CDKN2C Monoclonal Antibody (ZP001)

Catalog No.	Quantity
39-340-0	100 μg

Catalog No. 39-340-0 Supplier Invitrogen™ Supplier No. 393400

Description

Mouse Monoclonal Antibody

CDKN2C Monoclonal Antibody for Western Blot, ICC/IF, ELISA

The protein encoded by this gene is a member of the INK4 family of cyclin-dependent kinase inhibitors. This protein has been shown to interact with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression. Ectopic expression of this gene was shown to suppress the growth of human cells in a manner that appears to correlate with the presence of a wild-type RB1 function. Studies in the knockout mice suggested the roles of this gene in regulating spermatogenesis, as well as in suppressing tumorigenesis. Two alternatively spliced transcript variants of this gene, which encode an identical protein, have been reported.

Specifications

• Antigen: CDKN2C
• Applications: ELISA, Western Blot, Immunocytochemistry
• Classification: Monoclonal
• Clone: ZP001
• Concentration: 0.5 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 0.1% sodium azide; pH 7.4
• Gene: CDKN2C
• Gene Accession No.: P42773, Q60772
• Gene Alias: C77269; CDK6 inhibitor p18; Cdkn2c; CDKN6; cyclin dependent kinase inhibitor 2C; cyclin-dependent inhibitor; cyclin-dependent kinase 4 inhibitor C; Cyclin-dependent kinase 6 inhibitor; cyclin-dependent kinase 6 inhibitor p18; cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4); INK4c; p18; p18INK4c; p18-INK4c; p18-INK6
• Gene Symbols: CDKN2C
• Host Species: Mouse
• Immunogen: Recombinant, full-length mouse p18INK4c.
• Purification Method: Protein A
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 1031, 12580
• Target Species: Human, Mouse
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1 κ

Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov