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CDT1 Rabbit anti-Human, Polyclonal, Proteintech
SDP

Rabbit Polyclonal Antibody

$518.60

Specifications

Antigen CDT1
Concentration 0.25 mg/mL
Applications Immunocytochemistry, Immunofluorescence, Western Blot
Classification Polyclonal
Conjugate Unconjugated
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Products 1
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
50-172-9413
SDP
Encompass_Preferred
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Proteintech Group Inc
143821AP150UL
150 μL
Each of 1 for $518.60
Only null left
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Description

Description

KMT2A is a histone methyltransferase that plays an essential role in early development and hematopoiesis. It is a catalytic subunit of the MLL1/MLL complex, a multiprotein complex that mediates both methylation of ′Lys-4′ of histone H3 (H3K4me) complex and acetylation of ′Lys-16′ of histone H4 (H4K16ac). In the MLL1/MLL complex, KMT2A specifically mediates H3K4me, a tag for epigenetic transcriptional activation. KMT2A has weak methyltransferase activity by itself, and requires other components of the MLL1/MLL complex to obtain full methyltransferase activity. It has no activity toward histone H3 phosphorylated on ′Thr-3′, less activity toward H3 dimethylated on ′Arg-8′ or ′Lys-9′, and has higher activity toward H3 acetylated on ′Lys-9′. Required for transcriptional activation of HOXA9 and promotes PPP1R15A-induced apoptosis.
Specifications

Specifications

CDT1
Immunocytochemistry, Immunofluorescence, Western Blot
Unconjugated
Rabbit
Human
Q9H211
81620
CDT1 Fusion Protein Ag5810
Primary
-20°C
CDT1
0.25 mg/mL
Polyclonal
Liquid
RUO
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
CDT1, DNA replication factor Cdt1, Double parked homolog, DUP, RIS2
CDT1
IgG
Antigen Affinity Chromatography
Antibody
Videos
SDS
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Documents

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