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Invitrogen™ CEACAM8 Polyclonal Antibody
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Catalog No. PIPA5104296
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PIPA5104296 100 μL
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Catalog No. PIPA5104296 Supplier Invitrogen™ Supplier No. PA5104296
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total CEACAM8.

This gene encodes a member of the carcinoembryonic antigen (CEA) gene family, which belongs to the immunoglobulin superfamily. Two subgroups of the CEA family, the CEA cell adhesion molecules and the pregnancy-specific glycoproteins, are located within a 1.2 Mb cluster on the long arm of chromosome 19. Eleven pseudogenes of the CEA cell adhesion molecule subgroup are also found in the cluster. The encoded protein was originally described in bile ducts of liver as biliary glycoprotein. Subsequently, it was found to be a cell-cell adhesion molecule detected on leukocytes, epithelia, and endothelia. The encoded protein mediates cell adhesion via homophilic as well as heterophilic binding to other proteins of the subgroup. Multiple cellular activities have been attributed to the encoded protein, including roles in the differentiation and arrangement of tissue three-dimensional structure, angiogenesis, apoptosis, tumor suppression, metastasis, and the modulation of innate and adaptive immune responses. Multiple transcript variants encoding different isoforms have been reported, but the full-length nature of all variants has not been defined.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CEACAM8
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene CEACAM8
Gene Accession No. P31997
Gene Alias carcinoembryonic antigen CGM6; carcinoembryonic antigen gene family member 6; carcinoembryonic antigen related cell adhesion molecule 8; carcinoembryonic antigen-related cell adhesion molecule 8; CD66b; CD67; CD67 antigen; CEACAM8; CGM6; NCA-95; non-specific cross-reacting antigen NCA-95
Gene Symbols CEACAM8
Host Species Rabbit
Immunogen A synthesized peptide derived from human CEACAM8(Accession P31997), corresponding to amino acid residues G48-R98.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1088
Target Species Human, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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