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  6. Thermo Scientific Chemicals Cefotaxime sodium salt, 95%

Thermo Scientific Chemicals Cefotaxime sodium salt, 95%

Catalog No. AC454950250
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25 g
Packaging:
Glass Bottle
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AC454950250 25 g Glass Bottle
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Catalog No. AC454950250 Supplier Thermo Scientific Chemicals Supplier No. 454950250
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Description

Cefotaxime sodium salt, CAS # 64485-93-4, is the sodium salt form of cefotaxime with β-lactamase resistant antibiotic activity.

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Information

• The cefotaxime sodium salt is a - lactamase considered a third-generation cephalosporin with antibiotic and bactericidal activities
• This compound exerts its biological activity by binding to penicillin-binding proteins (PBP) located on the inner membrane of the bacterial cell wall leading to their inactivation. The inactivation of these proteins affects the cross-linking of peptidoglycan chains required for bacterial cell wall strength and rigidity, resulting in the weakening of cell walls and cell lysis.

Applications

• It is an efficient antibacterial compound that acts against gram-negative bacteria, without activity against gram-positive bacteria such as pseudomonas and penicillin-resistant strains of streptococcus pneumonia
• It has been used for plant cell culture and human cell lines in vitro
• Cefotaxime sodium salt has been used in antibiotic susceptibility testing (AST) methods
• Cefotaxime sodium salt is also used to remove bacteria from Ostreococcus tauri cultures

TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 64485-93-4
Molecular Formula C16H16N5NaO7S2
Molecular Weight (g/mol) 477.44
MDL Number MFCD00079073
InChI Key AZZMGZXNTDTSME-JUZDKLSSSA-M
PubChem CID 88631411
SMILES [Na+].CO\N=C(/C(=O)N[C@H]1[C@H]2SCC(COC(C)=O)=C(N2C1=O)C([O-])=O)C1=CSC(N)=N1

Specifications

Type Cefotaxime Sodium Salt
Melting Point 201.0°C to 210.0°C
Packaging Glass Bottle
Quantity 25 g
Assay Percent Range 95%
Solubility Information Solubility in water: soluble.
IUPAC Name sodium;(6S,7R)-3-(acetyloxymethyl)-7-[[2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
Formula Weight 477.44
Percent Purity 95%
Chemical Name or Material Cefotaxime sodium salt

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