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Thermo Scientific™ CellSensor™ SBE-bla HEK 293T Cell Line
Description
Smad cell signaling is a critical pathway involved in cell growth and proliferation. The CellSensor SBE-bla HEK 293T cell line is responsive to transforming growth factor-beta 1 (TGF-β1) and can be used to probe the Smad signaling pathway.The CellSensor SBE-bla HEK 293T cell line contains the β-lactamase reporter gene under the control of the Smad Binding Element (SBE). The SBE-bla construct was transduced into HEK 293T cells by lentivirus to obtain the cell line. Flow cytometry was used to isolate a clone responsive to TGF-β1 a dose response curve for this cell line using TGF-B1 is available in the validation packet data. Academic and non-profit customers, please inquire for special pricing.
Specifications
Specifications
| Assay Entry | Cell-based beta lactamase reporter gene |
| Cell State | Dividing Cells |
| Content And Storage | CellSensor™ Cell Lines are shipped on dry ice. Store in liquid nitrogen immediately upon receipt, or thaw for immediate use. |
| Product Line | CellSensor |
| Quantity | 1 Vial |
| Target Entry | TGF beta/BMP pathway, TGF beta R |
| Type | Cell Line |
| Cell Line | HEK 293T |
| System Type | CellSensor™ |
| Druggable Target | Signaling Pathway |
For Research Use Only. Not for use in diagnostic procedures.
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