Invitrogen™ CENPA Monoclonal Antibody (3-19)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA120832

Catalog No. PIMA120832

Description

Recommended positive controls: , BE cells. This antibody does not cross react with mouse CENPA proteins. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Centromeres are the differentiated chromosomal domains that specify the mitotic behavior of chromosomes. CENPA encodes a centromere protein which contains a histone H3 related histone fold domain that is required for targeting to the centromere. CENPA is proposed to be a component of a modified nucleosome or nucleosome-like structure in which it replaces 1 or both copies of conventional histone H3 in the (H3-H4)2 tetrameric core of the nucleosome particle.

Specifications

• Antigen: CENPA
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and no preservative; pH 7.2
• Gene Accession No.: P49450, Q6XXM1
• Gene Symbols: Cenpa
• Immunogen: Synthetic peptide: PRRRSRKPEAPRRRSPS, corresponding to amino acids 3-19 of Human CENP A.
• Quantity: 50 μg
• Primary or Secondary: Primary
• Target Species: Human, Chicken, C. elegans
• Product Type: Antibody
• Isotype: IgG1

• Applications: ChIP Assay, Immunohistochemistry (Paraffin), Neutralization, Western Blot, Immunocytochemistry
• Clone: 3-19
• Conjugate: Unconjugated
• Gene: Cenpa
• Gene Alias: CenH3; CENP A; CENPA; CENP-A; Centromere autoantigen A; centromere protein A; centromere protein A, 17kDa; centromere-specific histone; ggCENP-A; histone H3-like centromeric protein A; RGD1563607
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 100113359, 1058
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

Safety and Handling

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