Invitrogen™ CENPA Monoclonal Antibody (H.577.2)

Rabbit Monoclonal Antibody

Supplier:  Invitrogen™ MA514829

Catalog No. PIMA514829

Description

It is not recommended to aliquot this antibody. This antibody is not cross-reactive with other histone proteins, including Histone H3.

Centromeres are the differentiated chromosomal domains that specify the mitotic behavior of chromosomes. CENPA encodes a centromere protein which contains a histone H3 related histone fold domain that is required for targeting to the centromere. CENPA is proposed to be a component of a modified nucleosome or nucleosome-like structure in which it replaces 1 or both copies of conventional histone H3 in the (H3-H4)2 tetrameric core of the nucleosome particle.

Specifications

• Antigen: CENPA
• Classification: Monoclonal
• Concentration: 23.4 μg/mL
• Formulation: 0.01M HEPES with 100μg/mL BSA, 50% glycerol, 0.15M NaCl and <0.02% sodium azide; pH 7.5
• Gene Accession No.: O35216
• Gene Symbols: Cenpa
• Immunogen: Synthetic peptide corresponding to the amino terminus of mouse CENP-A protein.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Mouse
• Product Type: Antibody
• Isotype: IgG

• Applications: Immunoprecipitation, Western Blot, Immunocytochemistry
• Clone: H.577.2
• Conjugate: Unconjugated
• Gene: Cenpa
• Gene Alias: CenH3; CENP A; CENPA; CENP-A; Centromere autoantigen A; centromere protein A; centromere protein A, 17kDa; centromere-specific histone; ggCENP-A; histone H3-like centromeric protein A; RGD1563607
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 12615
• Content And Storage: -20°C
• Form: Liquid