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CENPO Mouse anti-Human, Clone: OTI7F9, lyophilized, TrueMAB™

Mouse Monoclonal Antibody
Supplier: OriGene CF809481

Description
Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO
Accurate chromosome segregation during mitosis requires a kinetochore to assemble correctly at the centromere of each chromatid and form a dynamic interface with the microtubules of the mitotic spindle. The kinetochore assembly includes the multisubunit CENP-H/I complex which can be divided into three functional classes based on phenotype analysis. One of these classes is referred to as the CENP-O class of proteins of which CENPO is the exemplar. These proteins form a stable complex with each other and are required for proper kinetochore function and for recovery from mitotic spindle damage. CENPO has also been shown to be an auto-antigen in a small population of anti-centromere antibodies- (ACA-) positive patients with sclerodoma.Specifications
CENPO | |
Monoclonal | |
Unconjugated | |
CENPO | |
CENP-O, ICEN-36, MCM21R | |
Mouse | |
Affinity Chromatography | |
RUO | |
79172 | |
-20° C, Avoid Freeze/Thaw Cycles | |
Lyophilized |
Western Blot | |
OTI7F9 | |
PBS with 8% trehalose and no preservative; pH 7.3 | |
Q9BU64 | |
CENPO | |
Human recombit protein fragment corresponding to amino acids 1-230 of human CENPO produced in E.coli. | |
100 μg | |
Primary | |
Human | |
Antibody | |
IgG2b |
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