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CENPO Mouse anti-Human, Clone: OTI7F9, lyophilized, TrueMAB™
SDP

Mouse Monoclonal Antibody

Supplier:  OriGene CF809481

Encompass_Preferred

Catalog No. 50-166-9525


May include imposed supplier surcharges.
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Description

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

Accurate chromosome segregation during mitosis requires a kinetochore to assemble correctly at the centromere of each chromatid and form a dynamic interface with the microtubules of the mitotic spindle. The kinetochore assembly includes the multisubunit CENP-H/I complex which can be divided into three functional classes based on phenotype analysis. One of these classes is referred to as the CENP-O class of proteins of which CENPO is the exemplar. These proteins form a stable complex with each other and are required for proper kinetochore function and for recovery from mitotic spindle damage. CENPO has also been shown to be an auto-antigen in a small population of anti-centromere antibodies- (ACA-) positive patients with sclerodoma.
Specifications

Specifications

CENPO
Monoclonal
Unconjugated
CENPO
CENP-O, ICEN-36, MCM21R
Mouse
Affinity Chromatography
RUO
79172
-20° C, Avoid Freeze/Thaw Cycles
Lyophilized
Western Blot
OTI7F9
PBS with 8% trehalose and no preservative; pH 7.3
Q9BU64
CENPO
Human recombit protein fragment corresponding to amino acids 1-230 of human CENPO produced in E.coli.
100 μg
Primary
Human
Antibody
IgG2b
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