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CENPO Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
SDP

Catalog No. 501732986 Shop All Proteintech Group Inc Products
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50-173-2986 150 μL
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Catalog No. 50-173-2986 Supplier Proteintech Group Inc Supplier No. 206111AP150UL
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Description

Rabbit Polyclonal Antibody

Accurate chromosome segregation during mitosis requires a kinetochore to assemble correctly at the centromere of each chromatid and form a dynamic interface with the microtubules of the mitotic spindle. The kinetochore assembly includes the multisubunit CENP-H/I complex which can be divided into three functional classes based on phenotype analysis. One of these classes is referred to as the CENP-O class of proteins of which CENPO is the exemplar. These proteins form a stable complex with each other and are required for proper kinetochore function and for recovery from mitotic spindle damage. CENPO has also been shown to be an auto-antigen in a small population of anti-centromere antibodies- (ACA-) positive patients with sclerodoma.

Specifications

Antigen CENPO
Applications Western Blot
Classification Polyclonal
Concentration 0.35 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene CENPO
Gene Accession No. Q8K015, Q9BU64
Gene Alias CENP O, CENPO, centromere protein O, ICEN36, MCM21R
Gene Symbols Cenpo
Host Species Rabbit
Immunogen CENPO Fusion Protein Ag14619
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 52504, 684439, 79172
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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