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Invitrogen™ CEP164 Monoclonal Antibody (17)
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Catalog No. PIMA531584
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100 μL
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Catalog No. Quantity
PIMA531584 100 μL
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Catalog No. PIMA531584 Supplier Invitrogen™ Supplier No. MA531584
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Description

Mouse Monoclonal Antibody

Positive Control: HeLa, A549.

CEP164 was initially identified as a centrosomal protein, but other studies have indicated that it also plays a role in the formation of primary cilia, the microtubule-based sensory antennae projecting from the surface of many eukaryotic cells as well as in DNA damage response acting as a mediator protein. CEP164 interacts with both ATR and ATM, proteins that trigger a number of cellular responses including the initiation of DNA damaged-induced cell cycle checkpoints. It is phosphorylated upon replication stress, ultraviolet (UV) radiation, and ionizing radiation silencing of CEP164 significantly reduces the DNA damage-induced phosphorylation of several proteins in the DNA damage-activated signaling cascade and compromises cell survival after UV damage. At least two isoforms of CEP164 are known to exist.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CEP164
Applications Immunoprecipitation, Western Blot
Classification Monoclonal
Clone 17
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative
Gene CEP164
Gene Accession No. Q9UPV0
Gene Alias AI450905; BC027092; ce164; centrosomal protein 164; centrosomal protein 164kDa; centrosomal protein of 164 kDa; Cep 164; CEP164; D030051D21; KIAA1052; mKIAA1052; NPHP15; RGD1560988; RGD1561243
Gene Symbols CEP164
Host Species Mouse
Purification Method Protein G
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 22897
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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