CEP164 Rabbit anti-Canine, Human, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-100-2833	Proteintech Group Inc 222271AP150UL	150 μL

Description

CEP164 was initially identified as a centrosomal protein, but other studies have indicated that it also plays a role in the formation of primary cilia, the microtubule-based sensory antennae projecting from the surface of many eukaryotic cells as well as in DNA damage response acting as a mediator protein. CEP164 interacts with both ATR and ATM, proteins that trigger a number of cellular responses including the initiation of DNA damaged-induced cell cycle checkpoints. It is phosphorylated upon replication stress, ultraviolet (UV) radiation, and ionizing radiation silencing of CEP164 significantly reduces the DNA damage-induced phosphorylation of several proteins in the DNA damage-activated signaling cascade and compromises cell survival after UV damage. At least two isoforms of CEP164 are known to exist.

Specifications

• Antigen: CEP164
• Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Canine, Human
• Gene Accession No.: Q9UPV0
• Gene ID (Entrez): 22897, 489389
• Immunogen: CEP164 Fusion Protein Ag17570
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: CEP164

• Concentration: 0.29 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Alias: centrosomal protein 164kDa, Centrosomal protein of 164 kDa, CEP164, KIAA1052
• Gene Symbols: CEP164
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody