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CEP78 Polyclonal Antibody, Bethyl Laboratories

Catalog No. p-7141101
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50-155-9746 20 μL
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Catalog No. 50-155-9746 Supplier Bethyl Laboratories, Inc Supplier No. A301800AT
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Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt.

This gene encodes a centrosomal protein that is both required for the regulation of centrosome-related events during the cell cycle, and required for ciliogenesis. The encoded protein has an N-terminal leucine-rich repeat (LRR) domain with six consecutive LRR repeats, and a C-terminal coiled-coil domain. It interacts with the N-terminal catalytic domain of polo-like kinase 4 (PLK4) and colocalizes with PLK4 to the distal end of the centriole. Naturally occurring mutations in this gene cause defects in primary cilia that result in retinal degeneration and sensorineural hearing loss which are associated with cone-rod degeneration disease as well as Usher syndrome. Low expression of this gene is associated with poor prognosis of colorectal cancer patients.

Specifications

Antigen CEP78
Applications Western Blot
Classification Polyclonal
Conjugate Unconjugated
Formulation TBS with 0.1% BSA and 0.09% sodium azide
Gene CEP78
Gene Accession No. Q5JTW2
Gene Alias C9orf81, IP63, centrosomal protein of 78 kDa
Gene Symbols CEP78
Host Species Rabbit
Immunogen Between 639 and 689
Purification Method Antigen affinity chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 84131
Target Species Human
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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