CEP89 Rabbit anti-Human, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Supplier:  Proteintech Group Inc 240021AP150UL

Catalog No. 50-173-4202

Description

24002-1-AP antibody recognizes all CEP123 isoforms.

CCDC123 (as known as CEP123), also named as CEP89, is a new player in the process of primary ciliogenesis and it also plays a role in mitochondrial metabolism where it may modulate complex IV activity. It has been shown that CEP123 is localized to the distal appendages of the mother centriole and the localization of CEP123 is cell cycle-dependent with its levels decreasing during mitosis. CEP123 depletion can cause defects in ciliary vesicle formation and prevent the formation of a ciliary vesicle at the distal end of the mother centriole. It is possible that CEP123 is involved in regulating the recruitment of membranes to the centrosome.

Specifications

• Antigen: CEP89
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CEP89
• Gene Alias: CCDC123, CEP123, CEP89
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 84902
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.22 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q96ST8
• Gene Symbols: CEP89
• Immunogen: CEP89 Fusion Protein Ag21206
• Quantity: 150 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG