Cephalothin sodium salt

Description

A first-generation cephalosporin antibiotic | CAS: 58-71-9 | C16H15N2NaO6S2 | 418.414 g/mol

Cephalothin sodium salt is used to study the mechanism of liposome encapsulated antibiotics1, strategies for co-opting β-lactamases of Gram-negative bacteria for treatment of antibiotics2, and for immunology studies in relation to antibiotics.3 It is used to study the effect of expression, binding and inhibition of penicillin-binding proteins especially PBP6 on bacterial cell wall mucopeptide synthesis.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Cephalothin sodium salt is used to study the mechanism of liposome encapsulated antibiotics1, strategies for co-opting β-lactamases of Gram-negative bacteria for treatment of antibiotics2, and for immunology studies in relation to antibiotics.3 It is used to study the effect of expression, binding and inhibition of penicillin-binding proteins especially PBP6 on bacterial cell wall mucopeptide synthesis.

Solubility
Soluble in water

Notes
Store away from strong oxidizing agents. Keep container tightly closed. Store in cool, dry conditions in well sealed containers.

Specifications

Chemical Identifiers

• CAS: 58-71-9
• Molecular Formula: C16H15N2NaO6S2
• Molecular Weight (g/mol): 418.414
• MDL Number: MFCD00072025
• InChI Key: VUFGUVLLDPOSBC-XRZFDKQNSA-M
• Synonym: 7-(2-Thienylacetamido)cephalosporanic acid sodium salt; Cephalotin sodium salt
• PubChem CID: 23675321
• ChEBI: CHEBI:3542
• IUPAC Name: sodium;(6R,7R)-3-(acetyloxymethyl)-8-oxo-7-[(2-thiophen-2-ylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
• SMILES: CC(=O)OCC1=C(N2C(C(C2=O)NC(=O)CC3=CC=CS3)SC1)C(=O)[O-].[Na+]

• Type: Cephalothin Sodium Salt
• Physical Form: Powder
• Odor: Odorless
• Color: White
• Quantity: 5 g
• Beilstein: 4120706
• Merck Index: 14,1982
• Solubility Information: Soluble in water
• Formula Weight: 418.42
• Chemical Name or Material: Cephalothin sodium salt

Safety and Handling

Hazard Category	H315-H317-H319-H334-H335
Hazard Statement	GHS H Statement H334-H317 May cause allergy or asthma symptoms or breathing difficulties if inhaled. May cause an allergic skin reaction.
Precautionary Statement	P261-P264b-P271-P272-P280-P285-P302+P352-P304+P340-P305+P351+P338-P333+P313-P342+P311-P362-P501c
EINECSNumber	200-394-6
RTECSNumber	XI0388300
TSCA	No
Recommended Storage	Keep cold

SDS

RUO – Research Use Only