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Ceranib 1, R&D Systems™
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Catalog No. 444850 Shop All Novus Biologicals Products
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Catalog No. Quantity
44-485-0 50 mg
44-481-0 10 mg
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Catalog No. 44-485-0 Supplier R&D Systems Supplier No. 4448/50

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Description

A Tocris product, part of R&D Systems. Ceramidase inhibitor; antiproliferative

Ceramidase inhibitor; inhibits proliferation in SKOV3 ovarian carcinoma cells (IC50 = 3.9 μM). Induces accumulation of ceramide species and decreases sphingosine and sphingosine-1-phosphate (S1P) levels in SKOV3 cells.

Chemical Identifiers

CAS 328076-61-5
Molecular Formula C26H21NO3
Molecular Weight (g/mol) 395.458
InChI Key OJMCCNQNCSCAJV-RVDMUPIBSA-N
Synonym ceranib 1, 3-3-4-methoxy-phenyl-acryloyl-6-methyl-4-phenyl-1h-quinolin-2-one, 3-2e-3-4-methoxyphenyl-1-oxo-2-propen-1-yl-6-methyl-4-phenyl-2 1h-quinolinone, 3-2e-3-4-methoxyphenyl prop-2-enoyl-6-methyl-4-phenyl-1h-quinolin-2-one, 3-e-3-4-methoxyphenyl prop-2-enoyl-6-methyl-4-phenyl-1h-quinolin-2-one
PubChem CID 5761166
IUPAC Name 3-[(E)-3-(4-methoxyphenyl)prop-2-enoyl]-6-methyl-4-phenyl-1H-quinolin-2-one
SMILES CC1=CC2=C(C=C1)NC(=O)C(=C2C3=CC=CC=C3)C(=O)C=CC4=CC=C(C=C4)OC

Specifications

Quantity 50 mg
Formula Weight 395.45
Percent Purity >98%
Product Line Tocris
Chemical Name or Material Ceranib 1

Safety and Handling

Recommended Storage Store at +4°C
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