Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Antibodies
  4. Primary Antibodies
  5. All Primary Antibodies
  6. PIPA558412

Invitrogen™ Cerebral Protein 1 Polyclonal Antibody
GREENER_CHOICE

Catalog No. PIPA558412
Change view
Click to view available options
Quantity:
100 μL
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
PIPA558412 100 μL
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
Catalog No. PIPA558412 Supplier Invitrogen™ Supplier No. PA558412
Only null left
Add to Cart
Add to Cart

Description

Rabbit Polyclonal Antibody

Immunogen sequence: AQRLFQEDPE AFLLYHRGFQ SQVKKWPLQP VDRIARDLRQ RPASLVVADF GCGDCRLASS IRNSVHCFDL ASLDPRVTVC DMAQVPLEDE SVDVAVFC Highest antigen sequence identity to the following orthologs: Mouse - 93%, Rat - 92%.

Essential component of the eNoSC (energy-dependent nucleolar silencing) complex, a complex that mediates silencing of rDNA in response to intracellular energy status and acts by recruiting histone-modifying enzymes. The eNoSC complex is able to sense the energy status of cell: upon glucose starvation, elevation of NAD(+)/NADP(+) ratio activates SIRT1, leading to histone H3 deacetylation followed by dimethylation of H3 at 'Lys-9' (H3K9me2) by SUV39H1 and the formation of silent chromatin in the rDNA locus. In the complex, RRP8 binds to H3K9me2 and probably acts as a methyltransferase. Its substrates are however unknown.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Cerebral Protein 1
Applications Immunohistochemistry (Paraffin), Immunocytochemistry
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Rrp8
Gene Accession No. O43159
Gene Alias 1500003O22Rik; 2900001K19Rik; AW538116; Cerebral protein 1; cerebral protein 1 homolog; HUCE1; hucep1; hucep-1; KIAA0409; NML; Nucleomethylin; RGD1308302; ribosomal RNA processing 8, methyltransferase, homolog (yeast); ribosomal RNA-processing protein 8; Rrp8; RRP-8; RRP8 methyltransferase homolog
Gene Symbols Rrp8
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human Cerebral Protein 1. Recombinant protein control fragment (Product #RP-97327).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 23378
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
Show More Show Less
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.