Cetirizine dihydrochloride, 99+%

Description

CAS: 83881-52-1 | C21H27Cl3N2O3 | 461.81 g/mol

Cetirizine dihydrochloride is used as a Histamine H-1 receptor antagonist, antihistaminic, piperazines. Inhibits activation of eosinophils and neutrophils. Non-sedating type histamine H1-receptor antagonist; major metabolite of hydroxyzine. Pharmacological activity resides primarily in the (R)-isomer.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Cetirizine dihydrochloride is used as a Histamine H-1 receptor antagonist, antihistaminic, piperazines. Inhibits activation of eosinophils and neutrophils. Non-sedating type histamine H1-receptor antagonist; major metabolite of hydroxyzine. Pharmacological activity resides primarily in the (R)-isomer.

Solubility
Soluble in water, DMSO, ethanol, and methanol.

Notes
Keep container tightly closed. Store away from oxidizing agents.

Specifications

Chemical Identifiers

• CAS: 83881-52-1
• Molecular Formula: C21H27Cl3N2O3
• Molecular Weight (g/mol): 461.81
• MDL Number: MFCD00941428
• InChI Key: PGLIUCLTXOYQMV-UHFFFAOYNA-N
• Synonym: cetirizine dihydrochloride, zyrtec, reactine, cetirizine hydrochloride, 2-2-4-4-chlorophenyl phenyl methyl piperazin-1-yl ethoxy acetic acid dihydrochloride, alerlisin, alercet, alergex, alertisin, cetriler
• PubChem CID: 55182
• IUPAC Name: dihydrogen 2-(2-{4-[(4-chlorophenyl)(phenyl)methyl]piperazin-1-yl}ethoxy)acetic acid dichloride
• SMILES: [H+].[H+].[Cl-].[Cl-].OC(=O)COCCN1CCN(CC1)C(C1=CC=CC=C1)C1=CC=C(Cl)C=C1

• Color: White
• Quantity: 10 g
• Merck Index: 14,2022
• Solubility Information: Soluble in water,DMSO,ethanol,and methanol.
• Formula Weight: 461.82
• Percent Purity: ≥99%
• Physical Form: Solid
• Chemical Name or Material: Cetirizine dihydrochloride

Safety and Handling

Hazard Category	H302
Hazard Statement	GHS H Statement H302 Harmful if swallowed.
Precautionary Statement	P264b-P270-P301+P312-P330-P501c
RTECSNumber	AG0980000
TSCA	No
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only