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Invitrogen™ cGKII Polyclonal Antibody
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Catalog No. PIPA552426
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100 μL
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Catalog No. Quantity
PIPA552426 100 μL
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Catalog No. PIPA552426 Supplier Invitrogen™ Supplier No. PA552426
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: REYHLKELRE QLSKQTVAIA ELTEELQNKC IQLNKLQDVV HMQGGSPLQA SPDKVPLEVH RKTSGLVSLH SRRGAKAGVS AEPTTRTYDL NKPPEFSFEK ARVRKDSSEK KLITDALNKN QFLKRLDPQQ IKDMVE Highest antigen sequence identity to the following orthologs: Mouse - 96%, Rat - 96%.

PRKG2 (PKG2, cGKII) exhibits many cellular functions and has cAMP- and cGMP-dependent protein kinase activity. cGKII is thought to play a key role in a diverse set of physiological pathway. cGKII may mediate intestinal secretion of water and electrolytes induced by the E. coli toxin STa and the intestinal peptide guanylin. Identification of the pathway that mediates intestinal fluid secretion by E. coli. cGKII is postulated to be a molecular switch that couples the cessation of proliferation and the start of hypertrophic chondrocyte differentiation through attenuating SOX9 function.
TRUSTED_SUSTAINABILITY

Specifications

Antigen cGKII
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene PRKG2
Gene Accession No. Q13237
Gene Alias AW212535; cGK 2; cGK2; cGKII; cGK-II; cGMP dependent protein kinase type II; cGMP-dependent protein kinase 2; cGMP-dependent protein kinase II; EC 2.7.11.12; GDPKII; PRKG2; PRKGR2; protein kinase cGMP- dependent type 2; protein kinase, cGMP- dependent, type 2; protein kinase, cGMP- dependent, type II; protein kinase, cGMP-dependent, type II; testicular tissue protein Li 99; type II cGMP-dependent protein kinase
Gene Symbols PRKG2
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human cGKII. Recombinant protein control fragment (Product #RP-102027).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5593
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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