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Apexbio Technology LLC LY 2365109 hydrochloride 1779796-27-8 50mg

Supplier: Apexbio Technology LLC B739450

LY 2365109 hydrochloride (CAS 1779796-27-8) is a selective inhibitor of glycine transporter 1 (GlyT1) functioning by specifically blocking GlyT1-mediated glycine uptake This inhibition leads to elevated glycine concentrations in the synaptic cleft thereby modulating NMDA receptor activity In cellular assays LY 2365109 hydrochloride has demonstrated nanomolar potency against human GlyT1 The compound serves as a valuable tool for investigating the physiological role of glycine transport pathways in the central nervous system and for exploring the involvement of GlyT1 in the mechanisms underlying neuropsychiatric disorders
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