Apexbio Technology LLC CGS 21680 HCl 124431-80-7 50mg

Supplier:  Apexbio Technology LLC B132450

CGS 21680 HCl is a selective agonist of the adenosine A2 receptor subtype which exerts its pharmacological effects through specific binding and activation of A2 receptors It demonstrates potent affinity for A2 receptors evidenced by its reported IC50 of approximately 22 nM in radioligand binding assays performed on rat striatal membranes It shows minimal interaction with other neurotransmitter binding sites such as adrenergic dopaminergic or serotonergic receptors In animal models administration of CGS 21680 HCl induces coronary vasodilation reduces blood pressure and exhibits transient increases in heart rate Therefore CGS 21680 HCl is frequently employed in cardiovascular and neurological research to evaluate adenosine receptor-mediated physiological processes and receptor signaling pathways

Catalog No. 50-000-62117