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Eurofins Discoverx CHIR 99021 (CT99021), 2 mg. (92-1116)
Supplier: Eurofins Discoverx 921116

CHIR-99021 HCl is a synthetic small molecule and ATP-competitive inhibitor of GSK3 kinase, with IC50 of 10 and 6.7 nM for GSK3α and GSK3β, respectively. Has >500-fold selectivity for GSK3 over closely related CDC2 and ERK2 kinases. Functions as a WNT activator. Provided as 2 mg of dry powder. These highly purified, pre-validated control ligands have been used to qualify our InCELL Hunter, PathHunter and cAMP Hunter cell lines as well as our Assay Ready Kits. Ligands are conveniently supplied with a recommended reconstitution buffer. For detailed information and product-specific datasheet, visit www.discoverx.com/ligands.
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