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Invitrogen™ Chitotriosidase Polyclonal Antibody
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Catalog No. PIPA547720
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100 μg
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PIPA547720 100 μg
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Catalog No. PIPA547720 Supplier Invitrogen™ Supplier No. PA547720
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Description

Sheep Polyclonal Antibody

In direct ELISAs and Western blots, approximately 30% cross-reactivity with recombinant human CHIT1 is observed. Reconstitute at 0.2 mg/mL in sterile PBS.

Chitotriosidase is secreted by activated human macrophages and is markedly elevated in plasma of Gaucher disease patients. The expression of chitotriosidase occurs only at a late stage of differentiation of monocytes to activated macrophages in culture. Human macrophages can synthesize a functional chitotriosidase, a highly conserved enzyme with a strongly regulated expression. This enzyme may play a role in the degradation of chitin-containing pathogens.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Chitotriosidase
Applications Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 5% trehalose and No Preservative
Gene CHIT1
Gene Accession No. Q9D7Q1
Gene Alias 2300002L19Rik; CHI3; CHIT; Chit1; CHITD; chitinase 1; chitinase 1 (chitotriosidase); chitinase-1; Chitotriosidase; Chitotriosidase-1; EC 3.2.1.14; FLJ00314; MGC125322; plasma methylumbelliferyl tetra-N-acetylchitotetraoside hydrolase
Gene Symbols CHIT1
Host Species Sheep
Immunogen Mouse myeloma cell line NS0-derived recombinant mouse Chitotriosidase/CHIT1 Ala22-Ser464.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 71884
Target Species Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Lyophilized
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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