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Chlorpromazine Hydrochloride, MP Biomedicals™

Catalog No. MP219032691 Shop All MP Biomedicals, Inc Products
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MP219032690 500 g
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Description

Inhibits calmodulin-dependent stimulation. Chlorpromazine Hydrochloride, MP Biomedicals is a phenothiazine antipsychotic and a D2 and H1 antagonist. It is a substitute for benzidine, o-dianisidine, and o-tolidine in the determination of microquantities of

Chlorpromazine Hydrochloride inhibits calmodulin-dependent stimulation of cyclic nucleotide phosphodiesterase and nitric oxide synthase, and it is reported to uncouple and inhibit oxidative phosphorylation at 10-3 – 10-4 M.

  • Demonstrates cytotoxic and antiproliferative activity against leukemic cells, but does not affect the viability of normal lymphocytes
  • Phenothiazine antipsychotic
  • D2 dopamine and H1 histamine receptors antagonist
  • Possibly a photo-genotoxic agent in humans
  • Helps to induce hypothermia in mice in the dose range of 12.5–100mg/kg
  • A substitute for benzidine, o-dianisidine, and o-tolidine in the determination of microquantities of hemoglobin and peroxidase
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 69-09-0
Molecular Formula C17H20Cl2N2S
Molecular Weight (g/mol) 355.321
InChI Key FBSMERQALIEGJT-UHFFFAOYSA-N
Synonym chlorpromazine hydrochloride, sonazine, chlorpromazine hcl, chloractil, klorpromex, promacid, hebanil, propaphenin, hibernal, hybernal
PubChem CID 6240
ChEBI CHEBI:3649
IUPAC Name 3-(2-chlorophenothiazin-10-yl)-N,N-dimethylpropan-1-amine;hydrochloride
SMILES CN(C)CCCN1C2=CC=CC=C2SC3=C1C=C(C=C3)Cl.Cl

Specifications

Melting Point 194°C to 199°C
Loss on Drying ≤1.0%
Quantity 1 kg
Solubility Information Soluble in water (50mg/mL - clear, colorless to faint yellow-grey solution), methanol, ethanol, chloroform; practically insoluble in ether, benzene.
Formula Weight 355.3g/mol
Physical Form Powder

Safety and Handling

Recommended Storage Store at Room Temperature (15–30°C)
WARNING: Reproductive Harm - www.P65Warnings.ca.gov
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