CHN2 Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Catalog No.	Quantity
50-173-2075	150 μL

Catalog No. 50-173-2075 Supplier Proteintech Group Inc Supplier No. 182591AP150UL

Description

Rabbit Polyclonal Antibody

This gene is a member of the chimerin family and encodes a protein with a phorbol-ester/DAG-type zinc finger, a Rho-GAP domain and an SH2 domain. This protein has GTPase-activating protein activity that is regulated by phospholipid binding and binding of diacylglycerol (DAG) induces translocation of the protein from the cytosol to the Golgi apparatus membrane. The protein plays a role in the proliferation and migration of smooth muscle cells. Decreased expression of this gene is associated with high-grade gliomas and breast tumors, and increased expression of this gene is associated with lymphomas. Mutations in this gene have been associated with schizophrenia in men. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Specifications

• Antigen: CHN2
• Applications: Western Blot
• Classification: Polyclonal
• Concentration: 0.13 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene: CHN2
• Gene Accession No.: P52757, Q80XD1
• Gene Alias: ARHGAP3, Beta chimaerin, Beta chimerin, chimerin (chimaerin) 2, CHN2, RHOGAP3
• Gene Symbols: Chn2
• Host Species: Rabbit
• Immunogen: CHN2 Fusion Protein Ag13106
• Purification Method: Antigen Affinity Chromatography
• Quantity: 150 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 1124, 69993
• Target Species: Human, Mouse
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG