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Invitrogen™ Cholera Toxin beta Monoclonal Antibody (2/63)
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Catalog No. PIMA183519
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200 μg
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Catalog No. Quantity
PIMA183519 200 μg
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Catalog No. PIMA183519 Supplier Invitrogen™ Supplier No. MA183519
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Description

Mouse Monoclonal Antibody

Mouse anti Cholera Toxin beta antibody, clone 2/63 detects the labile enterotoxin normally associated with V. cholera and reacts with an epitope on the B chain.No reactivity was observed with other species tested including various E. coli serotypes.

Cholera toxin (sometimes abbreviated to CTX, Ctx, or CT) is a protein complex secreted by the bacterium Vibrio cholerae. CTX is the causative agent of cholera infection. The alpha subunit contains two chains, A1 and A2, linked by a disulfide bridge. The alpha subunit activates the adenylate cyclase enzyme in cells of the intestinal mucosa leading to increased levels of intracellular cAMP. The beta subunit of cholera toxin binds to a GM1-ganglioside receptor which is widely accepted to initiate toxin action by triggering uptake and delivery of the toxin alpha subunit into cells. The holotoxin consists of a pentameric ring of beta subunits whose central pore is occupied by the alpha subunit.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Cholera Toxin beta
Applications ELISA, Immunohistochemistry (Frozen)
Classification Monoclonal
Clone 2/63
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide; pH 7.4
Gene Alias CTB; CTX; VC1456
Host Species Mouse
Immunogen Vibrio cholerae.
Purification Method Protein A
Quantity 200 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Bacteria
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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