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Invitrogen™ Chromogranin A Monoclonal Antibody (SP12)
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Catalog No. PIMA514536
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500 μL
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PIMA514536 500 μL
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Catalog No. PIMA514536 Supplier Invitrogen™ Supplier No. MA514536
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Description

Rabbit Monoclonal Antibody

MA5-14536 targets Chromogranin A in WB, and IHC (P) applications and shows reactivity with Human and Rat samples. This antibody does not cross-react with mouse tissues in IHC applications. The MA5-14536 immunogen is recombinant protein encoding human chromogranin A.

Chromogranin A (CHGA) is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. It is found in secretory vesicles of neurons and endocine cells. CHGA is a precursor to three biologically active peptides: vasostatin, pancreastatin, and parastatin. These peptides act as autocine or paracrine negative modulators of the neuroendocrine system. CHGA is an excellent marker for carcinoid tumors, pheo-chromocytomas, paragangliomas, and other neuro-endocrine tumors. Coexpression of chromogranin A and neuron specific enolase (NSE) is common in neuroendocrine neoplasms.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Chromogranin A
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone SP12
Concentration Conc. Not Determined
Conjugate Unconjugated
Formulation Tissue culture supernatant, TBS with 1% BSA and 0.1% sodium azide; pH 7.5
Gene Chga
Gene Accession No. P10354, P10645
Gene Alias AL-11; AL26; Beta-granin; betagranin (N-terminal fragment of chromogranin A); catestatin; CgA; CHGA; ChrA; chromofungin; chromogranin A; chromogranin A (parathyroid secretory protein 1); chromogranin A precursor; chromogranin-A; CTNNB; DKFZp686D02253; EA-92; ER-37; ES-43; FLJ25606; FLJ37923; GE-25; GR-44; GV-19; LF-19; LOW QUALITY PROTEIN: chromogranin-A; MGC105435; Pancreastatin; Parastatin; parathyroid secretory protein 1; p-Glu serpinin precursor; pituitary secretory protein I; Serpinin; Serpinin-RRG; SL21; SP-I; SS-18; Vasostatin I; Vasostatin II; Vasostatin-1; Vasostatin-2; WA-8; WE-14
Gene Symbols Chga
Host Species Rabbit
Immunogen Recombinant protein encoding human chromogranin A.
Quantity 500 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1113, 24258
Target Species Human, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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