Invitrogen™ CHST8 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA543412

Catalog No. PIPA543412

Description

Peptide sequence: GCSNWKRVLM VLAGLASSTA DIQHNTVHYG SALKRLDTFD RQGILHRLST Sequence homology: Cow: 86%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 86%; Rat: 100%.

The protein encoded by this gene belongs to the sulfotransferase 2 family. It is predominantly expressed in the pituitary gland, and is localized to the Golgi membrane. This protein catalyzes the transfer of sulfate to position 4 of non-reducing N-acetylgalactosamine (GalNAc) residues in both N-glycans and O-glycans. It is responsible for sulfation of GalNAc on luteinizing hormone (LH), which is required for production of the sex hormones. Mice lacking this enzyme, exhibit increased levels of circulating LH, and precocious sexual maturation of both male and female mice. Alternatively spliced transcript variants have been found for this gene.

Specifications

• Antigen: CHST8
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CHST8
• Gene Alias: 1500011J21Rik; AI426009; carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8; carbohydrate N-acetylgalactosamine 4-0 sulfotransferase 8; carbohydrate sulfotransferase 8; Chst8; GalNAc-4-O-sulfotransferase 1; GalNAc4ST; GALNAC4ST1; galNAc-4-ST1; galNAc4ST-1; N-acetylgalactosamine-4-O-sulfotransferase 1; PSS3
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 64377
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: Q9H2A9
• Gene Symbols: CHST8
• Immunogen: Synthetic peptide directed towards the middle region of human CHST8.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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